Meeting/Workshop

Neuromodulation in Psychiatry

February 10, 2023

Strasbourg (France)

INTRODUCTION

Dear colleagues,

We are pleased to invite you to the Neurex symposium on the personalization of non-invasive brain stimulation (NIBS) in neuropsychiatry that will be held in Strasbourg, France, February 10, 2023.

Recent advances in NIBS techniques have demonstrated their efficacy in treating psychiatric disorders. They also showed some limitations, such as those intrinsic to the one-size-fits-all targeting and stimulation methods. If we want NIBS to go beyond their own limits, we will have to take into consideration the heterogeneity of neuropsychiatric disorders in terms of targets and response to different stimulation protocols and technics, i.e., to enter into the era of precision / personalized medicine.

This question will be addressed along different axes.

1 - It seems necessary to go beyond the atheoretical and consensual diagnostic categories, derived from traditional classifications, and identify the pathophysiological mechanisms involved in the different subtypes of psychiatric disorders. Deep phenotyping and machine learning are potential tools for this paradigm shift.

2 - This comes with the development of new brain imaging acquisitions and analyses tools that could help the identification individualized specific targets for neuromodulation. Progress in individual functional imaging will be discussed (e.g., BOLD-connectivity, ASL-perfusion MRI, analysis of the brain dynamics).

3 - Personalized stimulation necessarily implies that the identified targets may actually be reached and modulated in the right way. Innovations in precision (e.g., neuronavigated robotized positioning, deep-stimulation techniques like focused ultrasound) and the on-line monitoring of the therapeutic effect (e.g., pre/post-EEG, online NIRS) are likely to change our future practice.

By bringing together experts in this rapidly evolving field, our ambition is to promote fruitful discussions and identify complementarities. We believe that if each contribution would already be an indisputable progress, the most decisive advances for our patients will come from their combination.

We hope that you could join us in this brainstorming symposium.

 

Dr Jack R. Foucher & Dr Ludovic C. Dormegny-Jeanjean

PROGRAM

The titles in italic below may potentially be modified.

 

8.00 – 8.30          Welcome

 Session 1 :          Focalized UltraSound

8.30 – 9.00          Marion Plaze / David Attali (Paris, France)

FUS neuromodulation, a French experience

 9.00 - 9.30          Máté Döbrössy (Freiburg, Germany) / Tiago Costa (Delft, Netherlands)

The vision of epidural focused ultrasound neuromodulation for Treatment-Resistant Depression

 9.30 – 10.00       Jonathan Vappou (Strasbourg, France)

FUS and indirect neuromodulation

 10.00 – 10.30     Coffee Break

 Session 2 : Personalization in neuromodulation 1

10.30 – 10.45     Ludovic Dormegny-Jeanjean (Strasbourg, France)

The use of imagery guided, robotized, rTMS in depression

 10.45 – 11.00     Clément de Crespin de Billy (Strasbourg, France)

The use of biomarkers in periodic catatonia

 11.00 - 12.00      John Rothwell (London, UK)

Metaplasticity and rTMS

 12.00 - 13.30      Lunch

 Session 3 : Meet the engineer and technology

Demonstration of robotic assistance for neuromodulation (at the CEMNIS, 2 groups [one with robot, one with cobot], 15min per demonstration)

 13.30 - 14.15      Axilum Robotics (Strasbourg, France)

Robotic assistance for rTMS - Axilum Robotics

 14.15 - 14.45      Michel Le Van Quyen (Paris, France)

In-ear EEG on the go to refine brain stimulation

 14.45 - 15.15      Paulo Loureiro de Sousa (Strasbourg, France)

Modelizing Electric current in MRI

 15.15 - 15.45      Coffee Break

 Session 4 : Guidage and personalization 2

15.45 - 16.30      Demian Battaglia (Strasbourg, France)

Stimulating the brain or stimulating a brain state? A collective dynamics point of view

 16.30 - 17.00      Jack Foucher (Strasbourg, France)

System based clinical phenotyping

 17.00 - 17.30      Nolan Williams (Palo Alto, US) - videoconference

The SAINT protocol and accelerated rTMS

 17.30 - 18.30       Round table (Jack Foucher, moderation)

DATES AND VENUE

February, 10th, 2022

Venue : lecture room to be announced soon

&

CEMNIS (for robot demonstration)

1 Pl. de l'Hôpital BP 426, 67091 Strasbourg

PLEASE NOTE THAT...

Neurex workshops are part of the cycle B5 of the University of Basel. They allow students to gain Credit Points from attending workshops/meetings.

This specific workshop will give rise to the attribution of 0.5 CP.

Important: Full rules & how to proceed available here.