Master internship

Master Traineeship in Neurodegeneration

Publication date: November 9, 2018

Location: Allschwil (Switzerland)

The objective of these 9 months traineeship starting ideally in January 2019 is to set up new models of Parkinson’s disease in mice. The practical work will consist in stereotaxic surgery to inject adeno-associated virus or proteins in mouse brain, followed by motor testing to detect potential deficits and finally necropsy and ex vivo analysis based on immunohistochemistry and Western Blot.<br /> <br /> <br /> Job Responsibilities<br /> • Actively contribute to the design of experimental strategy to set up Parkinson disease model in mice<br /> • perform stereotaxic surgery in mice<br /> • participate to the documented selection of relevant motor tests for the model and perform the tests<br /> • perform necropsy and sampling of relevant tissue (mainly brain), microdissection of specific brain regions may be needed<br /> • carry out ex vivo analysis (mainly immunohistochemistry and western blot)<br /> • responsible for the efficient planning, detailed analysis and accurate documentation of<br /> experiments and presentation of results in a multidisciplinary environment<br /> <br /> Candidate Requirements<br /> • Master student or lab technician with BSc or MS looking for experience to complement his/her training<br /> • recognized as an animal experimenter (LTK1 or equivalent)<br /> • experience in in vivo neurobiology (rodents behavioral pharmacology, stereotaxic surgery) is considered a plus<br /> • ability to plan, methodically perform, carefully analyze, accurately document experiments and present results<br /> • scientifically curious, willingness to learn new techniques and skills<br /> • flexible and motivated to work in a team<br /> • excellent knowledge of English (verbal and written)<br /> • good communication skills in a multicultural environment<br />
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